The Florey Institute
  • Home
  • News and Events
  • Research
  • The Team
  • Antimicrobial Resistance MSc
  • Contact

Day 4 - Testing new drugs to tackle corneal blindness

11/3/2019

15 Comments

 
Picture
As a first year PhD student, my research journey has only just begun. I’m based in the Department of Infection, Immunity & Cardiovascular Disease (IICD) and my focus is corneal infections.

The cornea is the transparent lens that covers the surface of our eyes and it plays an essential role in eyesight.  Therefore if bacteria infect the cornea, the results can be devastating and corneal infections are still a major cause of blindness worldwide. This type of infection is a particular problem in developing countries.

One of the major issues with treating corneal infections is that bacteria attach to the cornea as ‘biofilms’. A biofilm is a complex community of bacteria, held together in a sticky extracellular matrix. Bacteria within biofilms have different characteristics to free-living bacteria and one of these characteristics is an increased resistance to antibiotics. This makes it difficult to treat corneal infections and new antimicrobials are desperately required.

With this in mind, I am trying to develop an in vitro model of the infected cornea that can be used for drug testing. If successful, my PhD journey could end with the identification of new antimicrobials that are able to beat the biofilms and help to prevent corneal blindness.

Picture
An S. aureus biofilm:
These images were produced by my supervisor, Dr Rahaf Issa, using A Scanning Electron Microscope (SEM). The first image shows a biofilm early in its development and the second image shows a mature biofilm.


 
15 Comments
pay for essay reviews link
29/2/2020 06:16:20 am

The Summer Solstice is here, and I am excited for it. My family and I always do lots of stuff during this time, and it is always fun. I am hoping for a great one this year too. I have lots of things that I need to do, and believe me, I want all of it to be fun. I know that it is going to be hard for some people to enjoy this, and that is fine by me.

Reply
Facts about Las Vegas link
3/4/2020 04:38:25 pm



Article writing can't be easy for everyone, but you make it look like a piece of cake.By that I mean they should have character. Your article had character and is persuasive. Your views are very interesting.

Reply
en uygun uçak bileti link
1/7/2020 11:34:42 am

The more moments in the dietitian and increased the journey process and effective destination but it is so much more of a travel celebrate. I am looking back for the jumping on these live chats with students.

Reply
Tripuck link
10/9/2020 09:07:09 pm

Great Blog! I want to thank you for the struggles you have made in writing this post.

Reply
webstagram link
20/11/2020 04:58:01 am

Attractive, post. I just stumbled upon your weblog and wanted to say that I have liked browsing your blog posts. After all, I will surely subscribe to your feed, and I hope you will write again soon

Reply
먹튀검증 link
10/3/2021 12:40:09 pm

Your blog is too much amazing. I have found with ease what I was looking. Moreover, the content quality is awesome. Thanks for the nudge!

Reply
Real Estate Company Abu Dhabi link
29/3/2023 10:46:50 am

AZCB top Real Estate company in Abu Dhabi, UAE. Buy and Rent villas, apartments, offices best prices with Al Zaeem Commercial Brokers

Reply
cabinets and stone city link
5/4/2023 09:54:29 pm

Stones and Cabinets City delights our customers and makes them proud of their houses by making the complex simple. Our expert designers are dedicated to producing layouts that ensure your design is distinctive to our clients’ liking as well as functional.

Reply
Eye Injuries link
5/4/2023 10:03:14 pm

We are renowned for providing our patients with the most reasonably priced, painless medical care they have loved for years. Whether it’s a sports physical, routine physical, teen depression screening, or something else entirely,

Reply
About Us link
5/4/2023 10:06:06 pm

I-Cell Station identify your cell phone issues for free so that we can offer you the best possible solutions. We have expert-level solutions for all damaged cell phone devices, from screen replacements to charging ports and batteries, cameras speakers, back glass to motherboard level repairs.

Reply
Hormone for Weight Loss link
5/4/2023 10:09:37 pm

A blog is a discussion or informational website published on the World Wide Web consisting of discrete, often informal diary-style text entries. Posts are typically displayed in reverse chronological order so that the most recent post appears first, at the top of the web page

Reply
hfc chicken and pizza menu link
5/4/2023 10:12:28 pm

Click on the Order Online tab above and we'll deliver right to your office. And be sure to make use of our advance order feature to ensure that your food is delivered exactly when you want it.

Reply
house for rent in dha karachi link
5/4/2023 10:15:18 pm

Constructing a house in DHA (Defence Housing Authority) Karachi is a popular dream for many residents, as this well-planned area offers numerous facilities and modern amenities.

Reply
home remodeling experts link
5/4/2023 10:18:27 pm

If you’re looking for reliable and professional remodeling services, you can’t go wrong with us We’ve been serving homeowners and businesses in the area for years, and our experienced team knows how to get the job done right.

Reply
men's slim fit leather jacket link
18/4/2023 11:58:12 am

Allow designers and boutiques to place paid advertisements on your blog. · Charge designers and boutiques for blogging about their clothing and accessories.

Reply



Leave a Reply.

    News Feed
    Upcoming Events
    Past Events
    ​
    Picture

    News + Events Archives

    April 2021
    March 2020
    January 2020
    December 2019
    August 2019
    July 2019
    June 2019
    May 2019
    April 2019
    March 2019
    January 2019
    June 2018
    March 2018
    January 2018

    2017 - 2015

Picture
Picture
The University of Sheffield 
Western Bank 
Sheffield, South Yorkshire 
S10 2TN 

United Kingdom
The University of Sheffield | Research | Collaborate | Team | Jobs | Cookies policy | Privacy
Powered by Create your own unique website with customizable templates.

BACK TO TOP

© 2015 The University of Sheffield

© DivTag Templates Ltd | All Rights Reserved