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Gabriel Conway
Antimicrobial Resistance MSc student: 2020-2021

Email: 
GConway1@sheffield.ac.uk
Project Title: Combatting the mechanisms underlying antimicrobial-resistant typhoid fever with senolytic drugs



Background
I recently graduated from the University of Sheffield with a degree in Biochemistry. In the final year of my undergraduate degree, I conducted an extended research project under the supervision of Dr. Matthew Johnson which investigated the role of dynamic granal size in varying light conditions. During my final year, I developed an avid interest in infectious disease and the vast array of treatment techniques which fueled my decision to continue my studies in Sheffield, where I am currently undertaking a master’s degree in Antimicrobial Resistance.
 
In the coming term, I will be conducting a laboratory project with Dr. Dan Humphreys entitled ‘Combatting the mechanisms underlying antimicrobial-resistant typhoid fever with senolytic drugs’. The research aims to investigate the effects of typhoid toxins on host cell senescence and if a number of senolytic drugs could offer a novel route of antibacterial action via inhibition of the senescent phenotype. After this year I plan to enroll on the NHS’s Scientific Training Program where I can use my knowledge of antibiotic resistance and apply it to a clinical setting. 

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The University of Sheffield 
Western Bank 
Sheffield, South Yorkshire 
S10 2TN 

United Kingdom
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